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Carriers at higher risk of developing neurodegenerative disease

A team of Canadian scientists, including researchers at the Montreal Neurological Institute and Hospital (The Neuro) has discovered the first French-Canadian founder mutation gene linked to synucleinopathies, a group of neurodegenerative diseases that includes Parkinson鈥檚 disease (PD), dementia with Lewy-Bodies (DLB) and multiple system atrophy (MSA).

Classified as: MNI, genetics, Parkinson's disease, Healthy Brains for Healthy Lives, multiple system atrophy, Lewy-Bodies, PD, Ziv Gan-Or
Published on: 1 Oct 2018

To all members of the Faculty of Medicine,

Further to听last week鈥檚 update听on the McIntyre Medical Sciences Building, during which we confirmed the opening of the 5th and 6th floor amphitheatres and 2nd floor classrooms, we are pleased to report that the following additional areas will be opened as follows:

Published on: 10 Sep 2018

To all members of the Faculty of Medicine,

With the new academic year set to begin in earnest, I am pleased to report a great deal of progress has been made with respect to remediation efforts at the McIntyre Building following the July 13 fire. I take this opportunity to thank the University鈥檚 Project Review team who have taken over the reins from the Emergency Operations Committee and who continue their meticulous work to minimize disruptions to our community.

Please take note of the following updates:

Building Access:

Published on: 31 Aug 2018

When it comes to weight gain, the problem may be mostly in our heads, and our genes

Clinicians should consider how the way we think can make us vulnerable to obesity, and how obesity is genetically intertwined with brain structure and mental performance, according to new research.

Classified as: alain dagher, Uku Vainik, obesity, brain volume, MRI, human connectome project, PNAS
Published on: 28 Aug 2018

To all members of the Faculty of Medicine,

Published on: 10 Aug 2018

One of the tightest bottlenecks in vascular tissue engineering is the lack of strength and elasticity of engineered vascular wall models caused by limited elastic fiber deposition. In this study, collagen gel-based scaffolds were cellularised with vascular smooth muscle cells (SMCs) and supplemented with human plasma fibronectin (FN), a known master organizer of several extracellular matrix (ECM) fiber systems.

Classified as: department anatomy cell biology
Published on: 9 Aug 2018

Fibronectin is a protein that exists in vertebrates in two distinct forms: one present in the blood and the other in blood vessel walls. In mammals, fibronectin is important for the development of blood vessels before birth, but whether it is continuously required for blood vessel homeostasis from birth to adulthood is unknown. We present important results from three genetically modified mouse models, which show that at least one form of fibronectin is required for the proper function and integrity of blood vessels during this period.

Classified as: department anatomy cell biology
Published on: 8 Aug 2018

To all members of the Faculty of Medicine,

Following weeks of remediation efforts we continue to make steady progress on the road to returning the McIntyre Building to normal operations. Roughly half of the building has re-opened, with occupants of the 7th听floor and up returning to the building. A great deal of work remains however, in particular with respect to the lower floors. While the goal is to be able to re-open the 1st听to 6th听floors as quickly as possible, portions of these lower floors are expected to remain closed for several months.

Published on: 2 Aug 2018

To all members of the Faculty of Medicine,

As previously communicated, as of last Friday McIntyre Floors 7 and higher were reopened for all faculty and staff members and students, accessible via the 6th听floor Pine entrance. With three of the four ventilation systems servicing this area of the building returning to operation, temperatures on these floors continued to drop over the weekend and are now within their normal range, with the exception of small pockets of warmer areas that are serviced by the one HVAC system that remains to be cleaned.

Published on: 30 Jul 2018

To members of the Faculty of Medicine,

Published on: 28 Jul 2018

To all members of the Faculty of Medicine,

Published on: 27 Jul 2018

To听all听members of the Faculty of Medicine,

Work continues on plan, based on today鈥檚 update by 看片视频鈥檚 Emergency Operations听Centre (EOC).听Soot on Floors 7 to 13 has been cleaned from the majority of rooms and HVAC systems, and we have received the results of final air quality assessments to support the reopening on听Friday, July 27,听of Floors 7 to 13, provided the key steps outlined below are successfully completed.

Published on: 26 Jul 2018
To all members of the Faculty of Medicine,
Published on: 24 Jul 2018

To all members of the Faculty of Medicine,

Yesterday, a special information session was held to give the Faculty community a detailed account of the progress made since the McIntyre Building fire last Friday, July 13. At the meeting, 看片视频鈥檚 VP听(Administration and Finance)听Yves Beauchamp confirmed that the McIntyre will remain closed听until at least听Wednesday a.m., July 25. The goal, however,听is to听reopen portions of the building starting as early as Wednesday. In the meantime, please note that current protocols remain in place.

Published on: 20 Jul 2018

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