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Fackson Mwale

Academic title(s): 
  • Professor of Surgery;聽
  • Director of Clinical Innovation;聽
  • Course director of non-thesis;聽
  • Course director of Medical Technology Internship
Fackson Mwale
Contact Information
Email address: 
Fackson.mwale [at] mcgill.ca
Phone: 
(514) 340-8222 ext. 22948
Location: 
Lady Davies Institute for Medical Research - SMBD - Jewish General Hospital
Office: 
Room F-602
Division: 
Orthopaedics
Hospital title: 
Senior Investigator, Lady Davis Institute for Medical Research
Degree(s): 

Ph.D

Awards, honours, and fellowships: 

Dr. Mwale was recognized with the honorary status of Fellow of International Orthopaedic Research (FIOR) of the ICORS International College of Fellows.

His other honors include the Berton Rahn Prize Award, the Hansj枚rg Wyss Award, the North American Spine Society Award, and the North American Spine Society (NASS) Award.

He also received a certificate for starting the Research Interest Group and co-founding the Spine Research Community (comprising of more than 800 clinicians, basic scientists and fellows) at the Orthopedics Research Society in 2011 in Long Beach, California.

Current research: 
  • Tissue Engineering of Intervertebral Disc & Cartilage.
  • Role of the the calcium sensing receptor in the pathogenesis of osteoarthritis and intervertebral discs.

Clinical Interests: 

Intervertebral disc degeneration, back pain and osteoarthritis

Language(s) spoken: 
English
French
Spanish
Biography: 

Dr. Fackson Mwale is a Tenured Professor in the Dept. of Surgery at 看片视频 He is also a senior investigator at the Lady Davis Institute, past president of the Canadian Orthopaedic Research Society (CORS), Co-Founder of Trepso Therapeutics and Intervertech.

Dr. Mwale received his PhD from the University of South Carolina, followed by a Post-Doctoral fellowship at 看片视频 University with Dr. Robin Poole. Over the past 20 years, he has made fundamental contributions to research into the roles of the extracellular matrix in the growth plate, cartilage, bone and spine cell and molecular biology. His research has furthered our understanding of diseases from growth plate anomalies, osteoarthritis, and back pain. His studies have uncovered fundamental roles of Link N as a therapeutic agent for intervertebral discs and cartilage repair, mesenchymal tissue regeneration, as well as the calcium sensing receptor in the pathogenesis of osteoarthritis and intervertebral discs. Dr Mwale also developed PrimeGrowthTM Media system for the long-term culture of whole discs with vertebrae and PrimeGrowthTM disc cell medium and PrimeStemTM an optimized stem cell media which are now sold by Wisent Bioproducts.

Dr. Mwale has published over 100 papers in professional journals. He is a member of and has held leadership positions in several professional organizations, including the Spine Research Community (as one of the founders), and serves or has served on the editorial boards of several major journals, including European Cells and Material and JOR Spine. He currently serves as a grant reviewer at the CIHR and NIH study sections. He served as a member of the Skeletal Biology Structure and Regeneration [SBSR] study section and currently serves as a member of the Musculoskeletal Tissue Engineering Study Section, Center for Scientific Review. In 2018, he was one of the invited scientists to NIAMS in Washington to a round table with other experts in the field to discuss the future of spine research. He was recently selected to be a Spotlight speaker on Tissue engineering of intervertebral discs at the 67th Annual Meeting of the Orthopaedic Research Society in Long Beach, California, in 2021.

Dr. Mwale co-chaired the Canadian Connective Tissue Society twice in 2005 and 2011 and became the president. In 2010, he co-organized the Stem and Regenerative Workshop in Ottawa and the Spine Workshop in Kyoto, Japan, and he was the Co-organizer of the 2019 Combined Meeting of Orthopaedic Research Societies in Montreal, Canada.

Selected publications: 

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