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Integrated Clinical and Applied Biomedical Sciences

Research

Integrated clinical and applied biomedical sciences is an emerging area of excellence in the Faculty of Dental Medicine and Oral Health Sciences. Outstanding new researchers investigate nanometre-scale bone cements/biomaterials, synthetic tissue-engineered scaffoldings and controlled-release systems for bone reconstruction and salivary gland regeneration, and the bioactivation of implants by surface nanostructuring and protein nanopatterning.

Knowledge translation goals

Our research has a focus on bone replacement and regeneration, salivary gland replacement, implant fixation, and biosensors for patient diagnosis and treatment. More specifically, this research will: (1) allow for early detection of biochemical changes associated with disease and monitoring of wound healing; (2) provide new materials to repair mineralized tissues following trauma or elective surgery; (3) develop new regenerative strategies for oral and skeletal hard and soft tissues, thereby accelerating or inducing healing with an aim of faster patient recovery and faster restoration of function; (4) create cell-based therapies for the restoration of salivary gland function; and (5) create new strategies to integrate prostheses with bone, allowing new and improved oral implants to be designed and developed, with findings that may be translated to the cementless fixation of orthopaedic implants.

Researchers

Jake Barralet

  • Biomaterials
  • Drug delivery
  • Tissue regeneration

Maryam Tabrizian

  • Biomaterials
  • Biointerface
  • Biorecognition
  • Regenerative medicine
  • Nanomedicine
Simon Tran wearing a navy blazer, white shirt, black and beige tie, and glasses

Simon Tran

  • Tissue engineering
  • Stem cell
  • Saliva
  • Regenerative medicine
  • Translational research

Adjunct Professors听

man wearing light blue blazer, blue shirt and glasses

  • Periodontology
  • Implant dentistry
  • Biomaterials development听
  • Bone and tissue engineering听

Research collaborators: Clinical Research

Thomas Nguyen

  • Periodontology
  • Regenerative medicine
  • Implant dentistry
  • Artificial intelligence
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