¿´Æ¬ÊÓƵ

Robin Beech - Publications

Blanchard A, Gégnard F, Charvet C, et al. (2018) Deciphering anthelmintic targets from parasitic nematodes: when the model becomes the exception. PLOS Pathogens Submitted:

(2017) Genome-wide analysis of the cellulose synthase-like (Csl) gene family in bread wheat (Triticum aestivum L.). BMC Plant Biol 17: 193.

(2017) Diagnosis of resistance alleles in codon 167 of the beta-tubulin (Cya-tbb-1) gene from third-stage larvae of horse cyathostomins. Research in Veterinary Science 115: 92-95.

(2017) Comparative genomics of the major parasitic worms. bioRxiv

(2016) Characterisation of P-glycoprotein-9.1 in Haemonchus contortus. Parasite Vectors 9: 52.

(2016) Recent Duplication and Functional Divergence in Parasitic Nematode Levamisole-Sensitive Acetylcholine Receptors. PLoS Negl Trop Dis 10: e0004826.

Ìý(2015) Ivermectin binds toÌýHaemonchusÌýcontortusÌýtubulins and promotes stability of microtubules.ÌýInt J ParasitolÌý

(2015) Macrocyclic lactones and their relationship to the SNPs related to benzimidazole resistance. Molecular and Biochemical Parasitology 201: 128-134.

Ìý(2015) The evolution of pentameric ligand-gated ion-channels and the changing family of anthelmintic drug targets.ÌýParasitologyÌý142:Ìý303-17.

Ìý(2015) Monepantel irreversibly binds to and opens Haemonchus contortus MPTL-1 andÌýCaenorhabditisÌýelegansÌýACR-20 receptors.ÌýMolecular PharmacologyÌý87:Ìý96-102.

(2015) Functional Characterization of a Novel Class of Morantel-Sensitive Acetylcholine Receptors in Nematodes. PLoS Pathogens 11: e1005267.

Ìý(2015) Characterization of Haemonchus contortus P-glycoprotein-16 and its interaction with the macrocyclic lactone anthelmintics.ÌýMolecular and Biochemical ParasitologyÌý204:Ìý11-15.

Ìý(2015)ÌýHaemonchusÌýcontortusÌýP-glycoprotein-2: in situ localisation and characterisation of macrocyclic lactone transport.ÌýInternational Journal for ParasitologyÌý45:Ìý85-93.

(2015) Molecular basis for convergent evolution of glutamate recognition by pentameric ligand-gated ion channels. Sci Rep 5: 8558.

(2015) Genetic variability of Taenia saginata inferred from mitochondrial DNA sequences. Parasitology Research 114: 1365-76.

(2014) A dyf-7 haplotype causes sensory neuron defects and is associated with macrocyclic lactone resistance worldwide in the nematode parasite Haemonchus contortus. International Journal for Parasitology 44: 1063-71.

(2014) Recent advances in candidate-gene and whole-genome approaches to the discovery of anthelmintic resistance markers and the description of drug / receptor interactions. International Journal for Parasitology Drugs and Drug Resistance 4: 164-84.

(2014) Haemonchus contortus P-glycoproteins interact with host eosinophil granules: a novel insight into the role of ABC transporters in host-parasite interaction. PLoS One 9: e87802.

(2014) Novel assay for the detection and monitoring of levamisole resistance in Haemonchus contortus. Int J Parasitol 44: 235-41.

(2013) Characterization and comparative analysis of the complete Haemonchus contortus beta-tubulin gene family and implications for benzimidazole resistance in strongylid nematodes. International journal for parasitology 43: 465-75.

(2013) acr-23 Encodes a Monepantel-Sensitive Channel in Caenorhabditis elegans. PLoS pathogens 9: e1003524.

(2013) Cytochrome c oxidase subunit 1 and 12S ribosomal RNA characterization of Coenurus cerebralis from sheep in Iran. Vet Parasitol 197: 141-51.

(2013) Molecular and morphological characterization of the tapeworm Taenia hydatigena (Pallas, 1766) in sheep from Iran. J Helminthol 1-8.

Rostami S, Beech RN, Salavati R, Baneshi M, Kamyabi H and Fasihi Harandi M (2013) Morphometric analysis of larval rostellar hooks in Taenia multiceps of sheep in Iran and its association with mitochondrial gene variability. Iranian Journal of Parasitology 8: 579-85.

(2013) The genome and transcriptome of Haemonchus contortus, a key model parasite for drug and vaccine discovery. Genome biology 14: R88.

(2013) Molecular Cloning and Characterization of Novel Glutamate-Gated Chloride Channel Subunits from Schistosoma mansoni. PLoS pathogens 9: e1003586.

(2013) Characterization of cys-loop receptor genes involved in inhibitory amine neurotransmission in parasitic and free living nematodes. Parasitol Int 62: 599-605.

(2012) Levamisole receptors: a second awakening. Trends in parasitology 28: 289-96.

(2012) Nematode cys-loop GABA receptors: biological function, pharmacology and sites of action for anthelmintics. Invertebrate neuroscience 12: 3-12.

(2011) Annotation of two large contiguous regions from the Haemonchus contortus genome using RNA-seq and comparative analysis with Caenorhabditis elegans. PLoS One 6: e23216.

(2011) Anthelmintic resistance: markers for resistance, or susceptibility? Parasitology 138: 160-74.

(2010) Characterization of a novel tyramine-gated chloride channel from Haemonchus contortus. Molecular and biochemical parasitology 173: 64-8.

(2010) Genetic diversity of levamisole receptor subunits in parasitic nematode species and abbreviated transcripts associated with resistance. Pharmacogenetics and genomics 20: 414-25.

Beech RN, Zarlenga D, Bird D, Berriman M and Dent JA (2010) Naming genes beyond Caenorhabditis. Worm Breeder's Gazette 18: 17.

(2010) Nematode parasite genes: what's in a name? Trends in parasitology 26: 334-40.

Beech RN and Sylvestre A (2010) Mutations associated with anthelmintic drug resistance. Anti-Inf Agent Med Chem 9: 105-112.

(2010) Association of ion-channel genotype and macrocyclic lactone sensitivity traits in Haemonchus contortus. Molecular and biochemical parasitology 171: 74-80.

(2008) Isolation of mycoparasitic-related transcripts by SSH during interaction of the mycoparasite Stachybotrys elegans with its host Rhizoctonia solani. Current genetics 53: 67-80.

(2008) P-glycoprotein selection in strains of Haemonchus contortus resistant to benzimidazoles. Veterinary parasitology 152: 101-7.

(2007) Hypocholesterolaemic effects of plant sterol analogues are independent of ABCG5 and ABCG8 transporter expressions in hamsters. The British journal of nutrition 98: 550-5.

(2007) Population genetics of anthelmintic resistance in parasitic nematodes. Parasitology 134: 1133-47.

(2006) Ivermectin selection on beta-tubulin: evidence in Onchocerca volvulus and Haemonchus contortus. Molecular and biochemical parasitology 150: 229-35.

Back to top